The authors describe 2 patients who have had severely impaired sperm concentration and motility closely associated with the use of antidepressant medications.
They noted a temporal relationship between abnormal semen parameters and antidepressant therapy in these two patients. Each had normal semen parameters off medications.
The evaluation of each patient was unremarkable. While on antidepressant medications, both patients produced semen samples with marked impairment of sperm concentration and/or motility. Each patient demonstrated a normalization of sperm concentration and motility after discontinuation of antidepressants.
The authors hypothesize that Serotonin-reuptake inhibitor antidepressants may affect sperm transport, resulting in impaired sperm motility and concentration for some patients.
They noted a temporal relationship between abnormal semen parameters and antidepressant therapy in these two patients. Each had normal semen parameters off medications.
The evaluation of each patient was unremarkable. While on antidepressant medications, both patients produced semen samples with marked impairment of sperm concentration and/or motility. Each patient demonstrated a normalization of sperm concentration and motility after discontinuation of antidepressants.
The authors hypothesize that Serotonin-reuptake inhibitor antidepressants may affect sperm transport, resulting in impaired sperm motility and concentration for some patients.
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